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Role of Tranexamic acid in total joint arthroplasty.


Vasan Sinnadurai
Tranexamic acid (TXA) is an antifibrinolytic that reduces blood loss and transfusion rates in total joint arthroplasty. Blood loss and allogenic transfusion rates have been a challenge for surgeons performing total knee arthroplasty (TKA). The purpose was to evaluate the effect of TXA on blood loss, hemoglobin (Hb) changes, and transfusion in patients undergoing TKA and complications.